Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping
نویسندگان
چکیده
منابع مشابه
Miniaturized Real-Time PCR on a Q3 System for Rapid KRAS Genotyping
Colorectal cancer (CRC) is an aggressive human malignancy with a complex genomic landscape harboring KRAS mutations. In 40%-60% of patients with CRC, constantly active KRAS proteins affect the prognosis, surgical strategy, and clinical benefit from therapy with anti-epidermal growth factor receptor (EGFR) agents. For this reason, there is a greater demand for minimally-invasive diagnostic devic...
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ژورنال
عنوان ژورنال: Sensors
سال: 2017
ISSN: 1424-8220
DOI: 10.3390/s17040831